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Pevec D, Novinscak T, Brcic L, et al

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[7] It should not be used in individuals with hormone-sensitive tumors, such as prostate cancer or breast cancer, due to the risk of stimulating tumor growth through increased androgen or estrogen production

Alpha-CGRP-deficient mice display profoundly impaired bone regeneration characterized by a striking reduction in the number of bone-forming osteoblasts and a high rate of incomplete callus bridging and non-union